This journal focuses on the development and application of new approach methodologies (NAMs) and in vitro toxicology assays for chemical safety assessment. It covers the validation of alternative test methods for predicting endpoints such as eye irritation, skin sensitization, and endocrine disruption, often in the context of replacing or reducing animal testing. The scope also includes the integration of computational models, in silico tools, and advanced in vitro systems like reconstructed tissues and microphysiological systems to improve the understanding of chemical fate, exposure, and toxicological mechanisms.
Animal testing and alternativesComputational Drug Discovery MethodsEffects and risks of endocrine disrupting chemicals3D Printing in Biomedical ResearchContact Dermatitis and AllergiesAgricultural safety and regulationsPluripotent Stem Cells ResearchEnvironmental Toxicology and EcotoxicologyCarcinogens and Genotoxicity AssessmentImmunotoxicology and immune responses