Journal of Huntington's Disease

Aims & Scope✦ Inferred from recent articles

The Journal of Huntington's Disease focuses on Huntington's disease (HD), a hereditary neurodegenerative disorder. Research covers genetic factors, including repeat expansions and their instability, and their impact on diagnosis and risk prediction. The journal also investigates the disease's multidimensional burden on individuals and families, encompassing physical, emotional, and socioeconomic aspects across different countries. Studies explore the neurobiological underpinnings of HD, such as cellular pathology, transcriptomic changes in brain regions like the midcingulate cortex, and the role of somatic instability in neurodegeneration. Therapeutic strategies, including gene silencing and exercise-based rehabilitation, are examined, alongside diagnostic tools like advanced MRI techniques and antibody development. The journal also addresses clinical management, including weight and eating difficulties, end-of-life planning, and the quality of care in specialized settings, as well as the broader context of rare disease support and genetic counseling.

AI-summarised from recent articles · verify on the publisher page

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Source: OpenAlex · Note: citations accumulate over time so older years appear higher

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Subject Classification