npj Systems Biology and Applications considers all aspects of research covering computational and mathematical approaches to analysis and modeling of complex biological systems. The journal covers a broad range of topics including but not limited to: Computational modeling of biological systems Application of systems biology approaches to disease modeling, pharmacology, drug discovery, biotechnology, and industry Network biology and interactome analysis Multi-omics data integration Synthetic biology and metabolic engineering Single-cell systems biology Systems immunology and host-pathogen interactions Systems neuroscience and brain function Environmental systems biology Evolutionary systems biology The journal offers more choice to Nature Portfolio authors who are seeking a fully open-access and more inclusive platform for publishing their work. The journal is led by systems biology experts who collaborate to cultivate high-quality research. As part of the npj Series , this journal focuses on fostering global partnerships with the research community and other Springer Nature journals.
⚡ Speed vs Prestige
How does this journal balance review speed with impact level?
LOCKSS, PMC, Library of Congress; National Digital Preservation Program, China, CLOCKSS
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Plagiarism detection in place?
Yes
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Listed in DOAJ (verified OA)?
DOAJ verified
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Primary language documented?
English
Based on the Think.Check.Submit framework by DOAJ, COPE & OASPA. All data from verified open sources.
Publication & Citation Trend
Articles published
Times cited
2019
2020
2021
2022
2023
2024
2025
2026
Source: OpenAlex · Note: citations accumulate over time so older years appear higher
SJR Quartile by Discipline
Scimago ranks this journal separately in each subject category — its quartile can differ by discipline.
Applied MathematicsQ1
Biochemistry, Genetics and Molecular Biology (miscellaneous)Q1
Computer Science ApplicationsQ1
Drug DiscoveryQ1
Modeling and SimulationQ1
Subject Classification
Web of Science Categories
Mathematical & Computational Biology
Scopus Categories
Applied MathematicsDrug DiscoveryComputer Science ApplicationsBiochemistry, Genetics and Molecular Biology (miscellaneous)Modeling and Simulation
Research Topics (OpenAlex)
Gene Regulatory Network AnalysisBioinformatics and Genomic NetworksMicrobial Metabolic Engineering and BioproductionSingle-cell and spatial transcriptomicsComputational Drug Discovery MethodsMathematical Biology Tumor GrowthCell Image Analysis TechniquesGene expression and cancer classificationMetabolomics and Mass Spectrometry StudiesCancer Cells and Metastasis