This journal focuses on the development and application of nucleic acid-based therapeutics, including antisense oligonucleotides (ASOs), small interfering RNAs (siRNAs), and RNA editing technologies. Research covers chemical modifications, delivery methods, analytical techniques for quality control, and the evaluation of efficacy and safety, including immunogenicity and genotoxicity. Applications span various diseases, with a particular emphasis on genetic disorders, neuromuscular diseases, and metabolic conditions.
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RNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesDNA and Nucleic Acid ChemistryRNA and protein synthesis mechanismsCRISPR and Genetic EngineeringRNA Research and SplicingMicroRNA in disease regulationVirus-based gene therapy researchMuscle Physiology and DisordersRNA modifications and cancer